Предусмотренные в автомобиле Picasso боковая подушка безопасности призвана обезопасить голову и верхнюю часть туловища водителя. Однако во время испытаний на боковой удар в центральную стойку эта подушка смогла защитить туловище только до плеч. По этой причине комиссия Euro NCAP поставила лишь два балла за данный вид испытаний.

    SAFETY EQUIPMENT :: Driver and passenger dual-stage frontal airbags; side impact airbags; headprotecting curtain airbags; driver's knee airbag; front seatbelt dual pre-tensioners; front seatbelt load-limiters; ISOFIX and toptether anchorages in front passenger seat and all row 2 seats; front and rear seatbelt reminder system; ABS, ESP, emergency brake-assist (BAS), active speed-limiter.
    FRONTAL IMPACT :: The Picasso is fitted with a driver's knee airbag as standard. In such cases, manufacturers have the opportunity to demonstrate to Euro NCAP that the level of protection seen in the test is provided across the whole of the facia and for occupants of different weights and sizes. Euro NCAP considers some of the structures in the Picasso's dashboard to be a potential hazard to the driver's femurs as, in this case, Citroлn chose not to present evidence to the contrary.
    SIDE IMPACT :: The driver's chest lost a fraction of a point but the rounded score for side impact protection was a maximum 18.
    CHILD PROTECTION :: In the frontal impact, the rearward-facing child restraint tipped forward, exposing the head of the 1Ѕ year old dummy which then contacted the rear of the driver's seat. As a result, the car lost all points for the head protection of that dummy. The passenger's airbag can be disabled by means of a switch. However, information presented to the driver regarding the status of the airbag was not clear enough. The car was rewarded for being equipped with ISOFIX and top-tether anchorages in the front passenger seat and in all three seats in row 2 although the presence of those anchorages was not clearly indicated.
    SEATBELT REMINDER :: The Picasso is fitted with a seatbelt reminder system for the front and rear seats. The system for the front seats was satisfactory but the information presented regarding the status of the rear seatbelts was inadequate.
    PEDESTRIAN PROTECTION :: The bumper scored maximum points for the protection it offered to pedestrians' lower legs. The part of the bonnet likely to struck by a child's head was also rated predominantly 'fair'. However, that part of the bonnet which might be struck by an adult's head scored no points for the protection it offered.